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USE OF CURCUMIN ANALOGUE-2 GEL IN ADDITION TO TEETH CLEANING TO CURE SEVERE GUM DISEASES

EFFICACY OF CURCUMIN ANALOGUE-2 GEL AS A LOCAL DRUG DELIVERY AGENT IN THE TREATMENT OF CHRONIC PERIODONTITIS

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/09/046064
Enrollment
30
Registered
2022-09-30
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: CURCUMIN ANALOGUE-2 GEL: Curcumin analogue-2 gel is given as a local drug delivery agent, which is placed within the gingival sulcus at a dosage of 0.5mg. It is performed in a single ap

Sponsors

Dr Lingamaneni Krishna Prasad
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Age group of 30-60 years 2. Patients with Chronic Periodontitis 3. Probing Pocket Depth of 4 millimeter to 6 millimeter 4. Apparently systemically healthy individual 5. Individuals with minimum number of 20 teeth present in the oral cavity 6. Patients who are willing to give informed consent

Exclusion criteria

Exclusion criteria: 1. Previous history of any periodontal treatment in the past six months 2. Pregnancy and lactating mothers 3. Patients on high dose steroid therapy 4. History of previous or ongoing radiotherapy 5. Antibiotic therapy for the past six months 6. Smoking, Tobacco consumption and Orthodontic therapy 7. Patients having any systemic diseases such as diabetes

Design outcomes

Primary

MeasureTime frame
1. Improvement in clinical attachment level 2.Reduction of Periodontal Pocket Probing Depth Timepoint: Base line and 3 months

Secondary

MeasureTime frame
1. Reduction of Periodontal Pathogenic microbial countTimepoint: Base line and 3 months

Countries

India

Contacts

Public ContactDr D Ravindranath

Sibar Institute of Dental Sciences

ravident69@gmail.com9849222259

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026