Comparison of fixed versus individualized positive pressure ventilation technique in reducing respiratory complications following spinal deformity correction surgery.

Effect of Driving Pressure Guided PEEP Titration on Postoperative Pulmonary Complications in Patients Undergoing Scoliosis Correction Surgery: A Randomized Controlled Trial

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/09/046056

Enrollment

150

Registered

2022-09-30

Start date

Unknown

Completion date

Unknown

Last updated

2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: Q763- Congenital scoliosis due to congenital bony malformation Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: DRIVING PRESSURE GUIDED PEEP TITRATION: AFTER INDUCTION OF ANESTHESIA AND INTUBATION, INCREMENTAL PEEP TITRATION IS DONE TILL WE ACHIEVE MINIMAL DRIVING PRESSURE. PEEP IS INCREASED BY 1

Eligibility

Inclusion criteria

Inclusion criteria: 1. Parents willing to give consent for inclusion in study. 2. Patients aged between 6 and 18 years. 3. American society of anaesthesiology(ASA) physical status I or II. 4. Undergoing posterior spine fusion and instrumentation

Exclusion criteria

Exclusion criteria: 1. Parental refusal to participate in the study. 2. Patient with a cobbÃ¢â?¬•s angle >110Ã?Â°. 3. Patient with known severe lung disease. 4. Patient with history of previous thoracic surgery. 5. Patient undergoing anterior release/ growth rod insertion/ revision surgery for scoliosis. 6. Intra-operative massive blood loss [defined by blood loss >40ml/kg] or massive transfusion[ >8 unit of PRBC transfusion during surgery]

Design outcomes

Primary

Measure	Time frame
To compare the incidence of post-operative pulmonary complications in both the groups.Timepoint: 3rd Post-operative day	—

Secondary

Measure	Time frame
To compare intra-operative and post-operative oxygenation status.Timepoint: ABG done 1.Immediately after induction of anaesthesia 2.Before extubation with patient in supine position. 3.Twenty minutes post extubation in PACU;To compare intra-operative hypotension & bradycardia.Timepoint: Throughout surgery.;To compare length of hospital stay.Timepoint: Date of surgery to date of discharge;To compare postoperative atelectasis as assessed by lung ultrasoundTimepoint: Twenty minutes post extubation in PACU;To compare the incidence of postoperative radiological abnormality in chest Xray.Timepoint: Third post-operative day;To compare the number of patients requiring supplemental oxygen to maintain SPO2 more than 95%.Timepoint: Twenty minutes post extubation in PACU	—

Measure

Time frame

To compare intra-operative and post-operative oxygenation status.Timepoint: ABG done 1.Immediately after induction of anaesthesia 2.Before extubation with patient in supine position. 3.Twenty minutes post extubation in PACU;To compare intra-operative hypotension & bradycardia.Timepoint: Throughout surgery.;To compare length of hospital stay.Timepoint: Date of surgery to date of discharge;To compare postoperative atelectasis as assessed by lung ultrasoundTimepoint: Twenty minutes post extubation in PACU;To compare the incidence of postoperative radiological abnormality in chest Xray.Timepoint: Third post-operative day;To compare the number of patients requiring supplemental oxygen to maintain SPO2 more than 95%.Timepoint: Twenty minutes post extubation in PACU

—

Countries

India

Contacts

Public ContactDALIM KUMAR BAIDYA

ALL INDIA INSTITUTE OF MEDICAL SCIENCES

dalimkumar.ab8@gmail.com9871568534

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026