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Before prostate surgery give melatonin tablet to prevent loss in thinking and sensing ability in old patients

Exogenous Melatonin to prevent early postoperative Cognitive Dysfunctionin in elderly undergoing Transurethral Resection of Prostate Surgeries:A Randomised Controlled Trial. - RCT

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/09/045988
Enrollment
130
Registered
2022-09-28
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N401- Benign prostatic hyperplasia withlower urinary tract symptoms

Interventions

Intervention1: Giving Tab melatonine to study group in perioperative period: Eligible patient will be divided into two groups Study group will receive tab Melatonin 3mg HS ,on preoperative day and fo

Sponsors

Dr Rashmee Vijay Chavan
Lead Sponsor
Dr Anupama Sahasrabudhe
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: Inclusion criteria : 1. >60 yrs age patients undergoing elective TURP surgery 2.ASA I.II.III 3.Preop MMES score >23

Exclusion criteria

Exclusion criteria: 1.MMES score 1.5 hrs

Design outcomes

Primary

MeasureTime frame
Assessment : 1.On the day before surgery , MMSE score assessed 2.On the third postoperative day the patient will be assessed for 1. Cognitive function : MMSE score ( APPENDIX 1) ,2. Sedation score: (Ramsay sedation scale appendix 2) and 3. VAS score (appendix 3) before discharge . All patients will be followed up on 10 th post op day, during the follow -up visit will be assessed for MMSE . Timepoint: Assessment : 1.On the day before surgery , MMSE score assessed 2.On the third postoperative day the patient will be assessed for 1. Cognitive function : MMSE score ( APPENDIX 1) ,2. Sedation score: (Ramsay sedation scale appendix 2) and 3. VAS score (appendix 3) before discharge . All patients will be followed up on 10 th post op day, during the follow -up visit will be assessed for MMSE .

Secondary

MeasureTime frame
1. Assessment of quality of sleep 2. Assessment of analgesic requirementTimepoint: For 1,2, 3 and 10th postoperative day

Countries

India

Contacts

Public ContactDr Sahana N

D Y Patil Medical College,Kolhapur

rashmeevchavan@rediffmail.com9823243848

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026