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A study to examine the muscle weakness in intensive care unit patients

Early diagnosis of ICU acquired weakness in mechanically ventilated patients in intensive care unit

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2022/09/045883
Enrollment
385
Registered
2022-09-26
Start date
Unknown
Completion date
Unknown
Last updated
2023-09-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J962- Acute and chronic respiratory failure Health Condition 2: Z992- Dependence on renal dialysis Health Condition 3: Z991- Dependence on respirator Health Condition 4: G728- Other specified myopathies Health Condition 5: G628- Other specified polyneuropathies Health Condition 6: J99- Respiratory disorders in diseasesclassified elsewhere Health Condition 7: R652- Severe sepsis Health Condition 8: T794- Traumatic shock

Interventions

None listed

Sponsors

Manipal College of Health Professions
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients on mechanical ventilation in ICU for more than 48 hours APACHE II score more than 12

Exclusion criteria

Exclusion criteria: Diagnosed with pre existing neuromuscular disease Pregnancy Pre existing systemic vascular involvement such as systemic lupus erythematous Patients on inotropes. Dosage more than 5ml per hour Platelet count below 50,000 per microlitre

Design outcomes

Primary

MeasureTime frame
Percantage of people diagnosed with ICU acquired weakness based on MRC sum score Report at what day the patient developes weaknessTimepoint: First recording when the participant obeys 5 standardized questions which is followed by every day till the patient develops weakness or is discharged or discharged against medical advice or stops following commands or death

Secondary

MeasureTime frame
Number of days on mechanical ventilator, ICU stayTimepoint: When one of these events occur the patient develops weakness or is discharged or discharged against medical advice or stops following commands or death

Countries

India

Contacts

Public ContactAnup Bhat

Manipal College of Health Professions

arun.maiya@manipal.edu9845350823

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026