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Comparison of two inhalational anaesthesia drugs namely sevoflurane and desflurane using a parameter to measure the depth of anaesthesia

Comparison of the hypnotic potency of sevoflurane and desflurane using bispectral index at equi-minimum alveolar concentration

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/09/045869
Enrollment
80
Registered
2022-09-26
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Bispectral Index (BIS): A BIS-Quatroââ??¢ sensor (Covidien, Mansfield, MA, USA) will be placed on the forehead. The sensor consists of 4 connected parts. Part 1 will be applied at the

Sponsors

Praveen R
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ââ??? Patient with written informed consent ââ??? ASA physical status I and II

Exclusion criteria

Exclusion criteria: ââ?¬Â¢ Patient refusal ââ?¬Â¢ Known allergy to any one of the drugs used ââ?¬Â¢ Patients on hypnotics and antidepressants ââ?¬Â¢ Patients with neurologic or psychiatric disorders and cardiac diseases ââ?¬Â¢ Patients receiving Ã?²ââ?¬â??blocker drugs

Design outcomes

Primary

MeasureTime frame
To study any difference in BIS values at equi-MAC values of two inhalational agents. Timepoint: After induction, either of two inhalational agents (desflurane /sevoflurane) will be administered to achieve 1 MAC for 15 minutes duration to allow for equilibrium between alveoli, blood and brain. After this, BIS values will be measured at an interval of 1 minute for further 30 minutes� duration

Secondary

MeasureTime frame
To determine the change in Heart rate and MAP with the two inhalation agents Timepoint: After induction, either of two inhalational agents (desflurane /sevoflurane) will be administered to achieve 1 MAC for 15 minutes duration to allow for equilibrium between alveoli, blood and brain. After this, heart Rate and Blood pressure (MAP) values will be measured at an interval of 1 minute for further 30 minutes� duration

Countries

India

Contacts

Public ContactPraveen R

ESIC Medical College and PGIMSR

drpraveenramasamy@gmail.com8015167455

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026