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Comparison between two locally delivered drugs in gums for the treatment of pyorrhea

Comparative evaluation of Probiotic and Tetracycline fibers as an adjunctive to Non surgical Treatment of periodontitis- A randomized control study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/09/045816
Enrollment
24
Registered
2022-09-23
Start date
Unknown
Completion date
Unknown
Last updated
2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Probiotic Gel: It is defined as live microorganisms which when administered in adequate amounts confer a health benefit on the host The rationale for the use of probiotics in periodont

Sponsors

Dr Manali Gupte
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Having at minimum two teeth with one proximal site with (clinical attachment level [CAL]) of 3–4 mm and (probing pocket depth [PPD] of 5–6 mm) stage ll grade A.

Exclusion criteria

Exclusion criteria: Previous use of systemic or local antibiotic, anti-inflammatory drugs, probiotics, or periodontal therapy in the previous 6 month. Allergic to tetracycline. Smokers. Pregnant females. The different group of drug should not be administered in adjacent areas of tooth.

Design outcomes

Primary

MeasureTime frame
clinical parameter that is pocket probing depth, clinical attachment level and bleeding on probing and height and percentage of bone fill.Timepoint: Baseline,3 months and 6 months bone fill - baseline and 9 months

Secondary

MeasureTime frame
microbiological parameter ( colony forming unit -in porphynomonas gingivalis bacteria )Timepoint: at baseline, 3 months and 6 months

Countries

India

Contacts

Public ContactDr Jasuma Rai

K.M.Shah Dental college and Hospital

drjasumaj@gmail.com9974005760

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026