In order to increase mouth opening in Oral submucous fibrosis patients, ozonated olive oil was used to compare the wound healing and postoperative pain after scalpel and LASER fibrotomies.

Comparative evaluation of LASER fibrotomy and scalpel fibrotomy wound healing and postoperative pain using ozonated olive oil in relieving trismus in the oral submucous fibrosis patients.

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/09/045797

Enrollment

Registered

2022-09-23

Start date

Unknown

Completion date

Unknown

Last updated

2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K135- Oral submucous fibrosis

Interventions

Intervention1: LASER fibrotomy: Under local anesthesia, laser fibrotomy can be performed in one day in patients with moderate OSMF. Various lasers have been used by various authors for management of O

Eligibility

Inclusion criteria

Inclusion criteria: 1) The patients have not undergone any surgical treatment for OSMF. 2) The patients having inter-incisal mouth opening 20 mm or

Exclusion criteria

Exclusion criteria: 1) Patients with tempero-mandibular joint problems or trismus caused by something other than OSMF. 2) Immune-compromised patients and those with bleeding disorders. 3) Patients clinically diagnosed OSMF with leukoplakia, erythroplakia or lichenoid lesion and having other mucosal diseases.

Design outcomes

Primary

Measure	Time frame
Reduced postoperative pain and accelerated wound healingTimepoint: 3rd, 7th and 14th day after fibrotomy procedure	—

Secondary

Measure	Time frame
reduced trismusTimepoint: 3rd, 7th and 14th day after fibrotomy	—

Countries

India

Contacts

Public ContactPrasanna Sonar

SHARAD PAWAR DENTAL COLLEGE AND HOSPITAL, DATTA MEGHE INSTITUTE OF MEDICAL SCIENCES

artipanch@gmail.com9637430268

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026