Health Condition 1: F41- Other anxiety disorders
Conditions
Interventions
Intervention1: Yoga module: Yoga module validated for anxiety at NIMHANS Integrated Center for Yoga
More P, Kumar V, Usha Rani MR, Philip M, Manjunatha N, Varambally S, Gangadhar BN. Development, val
63:102776.PMID: 34571143.
The participants will have total of 6 sessions within period of two weeks.
Control Intervention1: Relaxation technique: Jacobsons Progressive Muscular Relaxation as practice
Sponsors
National Institute of Mental Health and Neurosciences
Eligibility
Inclusion criteria
Inclusion criteria: For patients: 1. Patients diagnosed with anxiety disorder except specific phobias and selective mutism as per ICD 11. 2. Patients with anxiety disorder who are on stable medications for at least 6 weeks. 3. Patients able to understand Hindi, English or Kannada language. 4. No history of alcohol or other substance dependence (except nicotine) in the last 6 months. 5. Between 18 to 60 years of age. 6. All genders. For healthy controls: 1. Between 18 to 60 years of age. 2. All genders. 3. Able to understand Hindi, English or Kannada language. 4. No history of alcohol or other substance dependence (except nicotine) in the last 6 months. 5. No history of anxiety disorder or any other long term psychiatric illness.
Exclusion criteria
Exclusion criteria: For patients: 1. Patients having specific phobias like agoraphobia and patients with selective mutism. 2. Patients having contraindication to Trans-cranial magnetic stimulation (TMS). [check list- Trans-cranial magnetic stimulation adult safety screen (TASS)] 3. Co-morbid substance abuse (excluding nicotine dependence), psychosis, mood disorders, suicidal and self-injurious behavior and mental retardation. 4. Ongoing current practice of yoga or any other mind-body techniques (e.g.; meditation, Tai-Chi, or related practices) of more than 45 minutes per week on average within the last 6 months or total estimated cumulative prior lifetime practice for more than 100 hours. 5. Presence of co-morbid neurological or general medical disorder that can alter mood states as clinically assessed. For healthy controls: 1. Presence of any psychiatric disorder as screened by PHQ-9 PRIME-MD (Patient Health Questionnaire) and assessed clinically. 2. Substance abuse (excluding nicotine dependence), psychosis, mood disorders, suicidal and self-injurious behavior and mental retardation. 3. Ongoing current practice of yoga or any other mind-body techniques (e.g.; meditation, Tai-Chi, or related practices) of more than 45 minutes per week on average within the last 6 months or total estimated cumulative prior lifetime practice for more than 100 hours. 4. Presence of neurological or general medical disorder that can alter mood states as clinically assessed.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Primary objective: To compare cortical inhibition parameters using Trans-cranial magnetic stimulation (TMS) between patients with anxiety disorder and Healthy controls. 2.Secondary Objective: Study the effect of yoga on GABAergic system by measuring cortical inhibition in patients with anxiety disorder after 6 sessions of yoga or progressive muscular relaxation. Timepoint: The cortical inhibition parameters will be measured at baseline and again after the 6 sessions of Yoga or Progressive Muscular Relaxation (PMR). | — |
Secondary
| Measure | Time frame |
|---|---|
| Comparison of anxiety scores between the groups before and after the intervention, using Hamilton Anxiety Rating Scale (HAM-A)Timepoint: Hamilton Anxiety Rating Scale (HAM-A) scores will be measured at baseline and again after 6 sessions of Yoga or Progressive Muscular Relaxation (PMR) | — |
Countries
India
Contacts
Public ContactDr Shivarama Varambally
National Institute of Mental Health and Neurosciences
Outcome results
None listed