Skip to content

This is a type of cancer found in elderly patients

A prospective observational cohort study to evaluate the effectiveness and toxicities of standard regimen in elderly patients with De-Novo DLBCL.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2022/09/045751
Enrollment
288
Registered
2022-09-21
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C851- Unspecified B-cell lymphoma

Interventions

Sponsors

Investigator initiated trial
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Inclusion Criteria 1. Newly diagnosed cases of Diffuse Large B cell Lymphoma 2. Age more than or equal to 60 years. 3. Patients who provide written informed consent

Exclusion criteria

Exclusion criteria: 1. None The patients found to meet all inclusion criteria of the study will thereafter be administered the informed consent process

Design outcomes

Primary

MeasureTime frame
Proportion of participants achieving complete response and partial response in clinical trial eligible and clinical trial ineligible cohort receiving RCHOP, will be measured.Timepoint: 6 months

Secondary

MeasureTime frame
Survival analysis will be calculated from the date of enrolment till the end of 1 year, data will be censored in case the patient is lost to follow-up. Timepoint: after completion of one year treatment;Comparison of dose modifications in all the treatment cohortsTimepoint: during the treatment;Comparison of grade III and grade IV toxicities in all treatment cohorts:Timepoint: during the treatment;Proportion of patients achieving complete and partial response in clinical trial ineligible and in clinical trial eligible cohort receiving RCEOP regimen.Timepoint: after completion of treatment;Proportion of patients in the clinical trial eligible cohort.Timepoint: after the enrollment

Countries

India

Contacts

Public ContactDr Hasmukh Jain

Tata Memorial Centre

dr.hkjain@gmail.com022241770007211

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026