Health Condition 1: K011- Impacted teeth
Conditions
Interventions
Intervention1: DEXMEDITOMIDINE HYDROCHLORIDE INJECTION 50mcg/0.5ml: Dexmedetomidine Hydrochloride Hikma Pharmaceuticals PLC (Hikma) is mixed with 0.9% Sodium Chloride Normal Saline Injection, 200mcg/
Sponsors
RAMADEVI MATTA
Eligibility
Inclusion criteria
Inclusion criteria: Patients of age 18 - 40 years Patients with bilaterally similar mandibular third molars Systemically healthy patients, ASA class I & II Patients willing to give an informed consent . Patients not receiving any medication that will alter the perception of pain.
Exclusion criteria
Exclusion criteria: Allergic to DEX Patients not willing to give an informed consent Acute inflammation or infection at the site of surgery Allergic rhinitis, nasal pathologies. Pregnant and lactating women. Bradycardia Renal or hepatic disease Using antipsychotic drugs, alpha blockers Patients with a BMI of more than 27 kg/m2
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain will be assessed preoperatively and postoperatively using VAS score. swelling and trismus. Sedation status will be assessed by a blinded observer with a modified Observerââ?¬â?¢s Assessment of Alertness/Sedation (OAA) scale --- after intranasal drug administration Timepoint: Pain will be assessed preoperatively and postoperatively using VAS score 1,6,12,24,48 hrs postoperatively. swelling and trismus assessed on 2nd and 7th postoperatively and Sedation status will be assessed by a blinded observer with a modified Observerââ?¬â?¢s Assessment of Alertness/Sedation (OAA) scale of 0 to 5 for every 10minutes to 90minutes after intranasal drug administration | — |
Secondary
| Measure | Time frame |
|---|---|
| Parametres monitored continously Heart Rate 3-lead electrocardiogram (ECG) and SpO2 Timepoint: Parametres monitored once in every 10 mins for 90 mins Blood pressure Respiratory Rate | — |
Countries
India
Contacts
Public ContactUSHIVAJI RAJU
VISHNU DENTAL COLLEGE
Outcome results
None listed