Health Condition 1: F322- Major depressive disorder, singleepisode, severe without psychotic features
Conditions
Interventions
Intervention1: Intramuscular injection Ketamine: Intramuscular Ketamine (0.5 mg per kg) will be on patients having suicidal ideations (MADRS SI more than 3) and repeat MADRS scale applied on 2hours po
Sponsors
NIL
Eligibility
Inclusion criteria
Inclusion criteria: 1. Having suicidal ideations (MADRS-SI score >3) 2. Who gave consent
Exclusion criteria
Exclusion criteria: 1. Present diagnosis or antecedents of clinically relevant cardiovascular disorders such as stroke, heart attack, etc. 2. Present or past diagnosis of glaucoma, intracranial hypertension. 3. Current diagnosis of schizophrenia as defined in the ICD-11. 4. Patients with any known hypersensitivity to ketamine. 5. patients who are hemodynamically unstable. 6. Delirious patients. 7. Pregnancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MADRS SI score, vitals, adverse events are to be checked to see effectiveness and safety of intramuscular ketamine (0.5 mg/k)Timepoint: baseline, 2 hours post injection, then on day 1,3,7,14,21,28.(1 month follow up) | — |
Secondary
| Measure | Time frame |
|---|---|
| not applicableTimepoint: not applicable | — |
Countries
India
Contacts
Public ContactMalika Sanspara
GMERS hospital, Gotri
Outcome results
None listed