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Comparison of three different Prophylactic Treatments for prevention of Postoperative Nausea and Vomiting (PONV) in patients undergoing surgery under general anaesthesia

Comparison of ramosetron, ondansetron and dexamethasone for the prevention of postoperative nausea and vomiting in patients undergoing surgery under general anaesthesia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/09/045664
Enrollment
90
Registered
2022-09-19
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K807- Calculus of gallbladder and bile duct without cholecystitis Health Condition 2: H708- Other mastoiditis and related conditions

Interventions

Control Intervention1: dexamethasone: Patients posted for surgeries like upper and lower abdominal surgeries and ENT surgeries under general anaesthesia during study period of oct 2020 to sept 2022 ar

Sponsors

SREE SINDHU SMITHA KONERU
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Age 18-60 years. 2. Patients who will be undergoing surgery under general anesthesia. 3. ASA class-I,II.

Exclusion criteria

Exclusion criteria: 1.Patients below 18 years and above 60 years 2.Patients with shock, hypotension. 3.History of allergy to ramosetron, ondansetron and dexamethasone.

Design outcomes

Primary

MeasureTime frame
compare the antiemetic efficacy of prophylactic intravenous administration of antiemetic drugs Ramosetron ,Ondensetron and Dexamethasone for prevention of Post operative nausea and vomiting.Timepoint: 24 hours—

Secondary

MeasureTime frame
1.To evaluate the need for rescue antiemetic after surgery. 2.Side effects and complication rates. Timepoint: 24 hours—

Countries

India

Contacts

Public ContactSREE SINDHU SMITHA KONERU

DR PINNAMANENI SIDDHARTHA INSTITUTE OF MEDICAL SCIENCES AND RESEARCH FOUNDATION

prem_swarup2007@yahoo.co.in9848134457

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026