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To assess the analgesic efficacy of Vitamin C in prevention of post operative sore throat occurring post tracheal intubation.

To evaluate the role of intra operative Vitamin C on severity of post operative sore throat following endotracheal intubation. - Vitamin C

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/09/045642
Enrollment
100
Registered
2022-09-19
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K800- Calculus of gallbladder with acutecholecystitis

Interventions

Intervention1: Intravenous injection Vitamin C.: inj. vitmin C given in 500ml of normal saline over a period of 30 minutes intra operatively after endotracheal intubation and continue to follow up alo

Sponsors

Pandit BD Sharma PGIMS Rohtak
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: After obtaining informed and written consent, adult patients between age 18ââ?¬â??60Ã? years, ASA physical status I and II and Mallampati class 1& 2 undergoing elective surgical procedures under general anaesthesia requiring endotracheal intubation which are having successful intubation in single attempt will be included in this study.

Exclusion criteria

Exclusion criteria: 1. H/O sore throat, sinusitis, upper respiratory tract infections. 2. Prolonged surgeries i.e. Duration of >3 hours. 3. Upper gastro-intestinal surgeries and patient with gastro-esophageal reflux disease. 4. Difficult intubation. 5. Patients undergoing day case, bariatric, cardiac, nasal, dental, oral or head & neck surgeries, requiring placement of throat pack or nasogastric/ orogastric tube, 6. Any H/O of severe medical illness 7. Allergic to Vitamin C. 8. Pregnant and lactating females 9. Psychiatric disorders will be excluded from the study. 10. Steroid therapy.

Design outcomes

Primary

MeasureTime frame
To assess severity of throat pain using VAS score occurring post endotracheal intubation.Timepoint: Followed up in recovery room and surgical ward for next 24 hours.—

Secondary

MeasureTime frame
Consumption of total amount of postoperative analgesia and its Side effect if any.Timepoint: Followed up in recovery room and surgical ward for next 24 hours.—

Countries

India

Contacts

Public ContactIshan Singh Kagra

Pandit B.D. Sharma PGIMS,Rohtak

singhishan1030@gmail.com8059663738

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026