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Comparison between two drugs,intravenous lignocaine and intravenous magnesium sulphate for decreasing fluctuations of blood pressure, pulse rate during initiation of surgery in patients going for abdominal surgeries.

A comparative study between intravenous lignocaine versus intravenous magnesium sulphate for attenuation of haemodynamic stress response during laryngoscopy and tracheal intubation in abdominal surgeries.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/09/045555
Enrollment
120
Registered
2022-09-15
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Intravenous Magnesium sulphate: A total 120 patients will be enrolled for the study after obtaining a written consent from these patients. These patients will be randomly allocated by r

Sponsors

RAMAKRISHNA MISSION SEVA PRATISHTHAN
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: a Patients posted for surgeries under general anaesthesia b Patients with ASA Class I and II

Exclusion criteria

Exclusion criteria: a Known allergy to anaesthetic agents b History of a major psychiatric disorder c History of substance abuse and current opioid use d Anticipated difficult intubation e Patients on beta blockers f Baseline systolic blood pressure (SBP) less than 100 mm Hg g Compensatory Tachycardia h Pregnancy i Diabetic Patients j Hypertensive patients on medication

Design outcomes

Primary

MeasureTime frame
Comparison of attenuation of haemodynamic response during induction of general anesthesia between intravenous magnesium sulphate and lignocaine to compare: HR SBP DBP Any adverse drug reactionTimepoint: will be recorded at intubation and 1, 2, 4,6,8, 10 minutes after intubation.—

Secondary

MeasureTime frame
Comparison of attenuation of haemodynamic response including,MAP & RPP during induction of general anesthesia between intravenous magnesium sulphate and lignocaineTimepoint: Hemodynamic parameters including MAP & RPP and any adverse effect will be recorded at intubation and 1, 2, 4,6,8, 10 minutes after intubation.—

Countries

India

Contacts

Public ContactINDRANI CHAKRABORTY MITRA

Ramakrishna Mission Seva Pratisthan Vivekananda Institute Of Medical Sciences,Kolkata

indranimitra7@gmail.com9830662797

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026