Health Condition 1: I251- Atherosclerotic heart disease of native coronary artery
Conditions
Interventions
Intervention1: Heartfulness meditation practices: Patients enrolled in study are introduced to the 3 day heartfulness mediation process which is being conducted for a duration of 1 hour daily on three
Sponsors
Sri Balaji Arogya Varaprasadini Scheme
Eligibility
Inclusion criteria
Inclusion criteria: INCLUSION CRITERIA: All patients of either sex with age >30 years and 1. Did not undergone percutaneous coronary revascularization 2. Did not undergone coronary artery bypass grafting (CABG) 3. Are willing to participate in the study
Exclusion criteria
Exclusion criteria: EXCLUSION CRITERIA: 1. Patients who had already undergone percutaneous coronary revascularization or CABG 2. Patients with acute coronary syndrome. 3. Patients with significant left main coronary artery stenosis. 4. Patients with ejection fraction 5. Patients with moderate to severe ischaemic mitral regurgitation. 6. Patients with moderate to severe pulmonary arterial hypertension 7. Patients with structural heart disease 8. Patients with decompensated heart failure 9. Patients with renal impairment 10. Patients with known malignancies 11. Pregnant women 12. Patients already practicing any form of meditation 13. Patients not willing to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Effect of heartfulness meditation practices for four months compared to baseline (before start of intervention) on 1. Change in brachial artery reactivity to flow mediated dilatation 2. Change in blood levels of inflammatory markers - hsCRP and IL-6 3. Change in gene expression of IL-6 geneTimepoint: At baseline (before intervention) and at four months after intervention | — |
Secondary
| Measure | Time frame |
|---|---|
| Effect of heartfulness meditation practices for four months compared to baseline (before start of intervention) on 1. Change in quality of life (QOL) and selected wellbeing parameters using questionnaires â?? WHOQOL BREF (WHO Quality Of Life Brief questionnaire), Mental Health Continuum Short Form (MHC-SF), Depression, Anxiety & Stress Scale (DASS 21). 2. Change in carotid intimal medial thickness and carotid plaque score by carotid Doppler.Timepoint: At baseline (before intervention) and at four months after intervention | — |
Countries
India
Contacts
Public ContactDr Vijaya Chandra Reddy Konda
Sri Venkateswara Institute of Medical Sciences
Outcome results
None listed