Health Condition 1: J00-J99- Diseases of the respiratory system
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) Age more than 18 years 2) Mechanical ventilation of at least 48 hours 3) Patient should met the following criteria for readiness of weaning: ? Oxygenation status: FiO2 200 ? Ventilation status: Respiratory rate less than or equal to 30/min & paCO2 of ? Stable hemodynamics ? Intact mentation ? Minimal secretion and effective cough
Exclusion criteria
Exclusion criteria: 1) Known Neuromuscular disorder 2) Known case of diaphragmatic paralysis 3) Tracheostomized patients 4) Increased Intraabdominal Pressure 5) Phrenic Nerve Palsy 6) Obstetric antenatal patients
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess and compare the effectiveness of predicting weaning success of DTF with CORE index and Integrated weaning index Timepoint: After 48 hours of initiation of mechanical ventilation and with pressure support of 8 and 5 cmH2o during weaning | — |
Secondary
| Measure | Time frame |
|---|---|
| To calculate the cut-off value for optimal DTF to succeed weaning at different time points after initiation of mechanical ventilationTimepoint: 48 hours, 5th day, 7 th day, 10 and 14 th day | — |
Countries
India
Contacts
Jawahralal Institute of Postgraduate medical education and research