Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Intranasal dexmedetomidine: Group N- will receive intranasal dexmedetomidine 1 mcg/kg
undiluted parenteral preparation (100mcg/ml), equally divided volume instilled into both nostrils after giving general anesthesia
Control Intervention1: caudal block: Group C- will receive 1 mcg/kg de
Sponsors
All India Institute of Medical Sciences New Delhi
Eligibility
Inclusion criteria
Inclusion criteria: patient Aged 1-8 years, ASA physical status I/II, undergoing infraumbilical surgeries under general anaesthesia
Exclusion criteria
Exclusion criteria: 1. Parental /guardian refusal for inclusion in the study 2. Known allergy to amide local anaesthetics or dexmedetomidine. 3. Pre-existing cardiovascular, respiratory or neurological disease 4. History of developmental delay or mental retardation which could make observational pain intensity assessment difficult 5. Children with conduction blocks 6. Known or suspected coagulopathy 7. Anatomical abnormalities of spine and sacrum. 8. Local infection at caudal puncture site 9. Rhinitis and nasal polyp 10. Patients with age 7 years 11. ASA grade III/IV
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the duration of postoperative analgesia ie. the time when the first analgesic is required postoperativelyTimepoint: Immediate postoperative to over 24 hours after surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare the following parameters between 2 groups 1. Postoperative emergence delirium using WATCHA score 2. Postoperative sedation using 4-point sedation score 3. Modified Aldrete score 6 hrs postoperatively 4. Total analgesic consumption in first 24 hrs 5. Incidence of side effects like bradycardia , hypotension , nausea-vomiting and desaturation, urinary retention Timepoint: 24 hrs postoperatively | — |
Countries
India
Contacts
Public ContactAyushi Agarwal
All India Institute of Medical Sciences,New Delhi
Outcome results
None listed