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A clinical trial to study the effect of two drugs, dexamethasone and dexmedetomidine given as a regional anesthesia in patients undergoing surgeries for forearm and hand.

COMPARATIVE STUDY OF DEXAMETHASONE AND DEXMEDETOMIDINE AS ADJUVANTS TO 0.5% ROPIVACAINE IN AXILLARY BLOCK. A PROSPECTIVE RANDOMIZED CONTROLLED DOUBLE BLIND STUDY

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/09/045450
Enrollment
78
Registered
2022-09-13
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M719- Bursopathy, unspecified Health Condition 2: M200- Deformity of finger(s) Health Condition 3: M849- Disorder of continuity of bone, unspecified Health Condition 4: M674- Ganglion Health Condition 5: L99- Other disorders of skin and subcutaneous tissue in diseases classified elsewhere Health Condition 6: M679- Unspecified disorder of synovium and tendon

Interventions

Intervention1: ROPIVACAINE WITH DEXAMETHASONE: 30ML OF 0.5% ROPIVACAINE AND 2ML OF DEXAMETHASONE (8MG) ADMINISTERED IN AXILLARY BRACHAIL PLEXUS BLOCK Intervention2: ROPIVACAINE WITH DEXMEDETOMIDINE: 3

Sponsors

MANIPAL HOSPITAL BANGALORE
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA 1 & 2 ELECTIVE ELBOW, FOREARM, WRIST AND HAND SURGERIES UNDER AXILLARY BRACHIAL PLEXUS BLOCK

Exclusion criteria

Exclusion criteria: ALLERGY TO DRUGS USED IN THE STUDY HISTORY OF LONGTERM OPIOIDS OR OTHER ANALGESIC CONSUMPTIONS PATIENTS ON SYSTEMIC CORTICOSTEROIDS FOR 2WEEKS OR MORE WITHIN 6MONTHS OF SURGERY PATIENTS WITH BLEEDING OR COAGULATION DISORDERS PATINETS WITH ANY NEUROLOGICAL OR MUSCULOSKELETAL DISORDERS ANY CONTRAINDICATIONS FOR BLOCKS USED IN THE STUDY INFECTION OF LESION AT THE SITE OF THE BLOCK TECHNICAL FAILURE OF THE BLOCK PREGNANT PATIENTS, PATIENTS WITH HEART BLOCK, HYPOTENSION, BRADYCARDIA, CARDIAC FAILURE

Design outcomes

Primary

MeasureTime frame
TO FINDOUT WHETHER DEXAMETHASONE AND DEXMEDETOMIDINE WHEN COMBINED WITH 0.5% ROPIVACAINE PROLONG THE DURATION OF SENSORY AND MOTOR BLOCKTimepoint: 24HOURS—

Secondary

MeasureTime frame
EFFECT ON ONSET OF ACTIONTimepoint: 24HOURS;EFFECT ON PATIENT SATISFACTIONTimepoint: 24HOURS;EFFECT ON POST OPERATIVE ANALGESIC REQUIREMENTSTimepoint: 24HOURS;INCIDENCE OF BRADYCARDIA, HYPOTENSION AND ARRHYTHMIASTimepoint: 24HOURS—

Countries

India

Contacts

Public ContactSHIVANANDA N V

MANIPAL HOSPITAL WHITEFIELD

shivananda.nadiminti@gmail.com9686585584

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026