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Study to check the efficacy of Buprenorphine Patch 10mg in controlling the Blood Pressure and Heart Rate that increases in response to introduction of Laryngoscope and Endotracheal Tube into the airway in patients undergoing Surgery under General Anesthesia

Attenuation of stress response to laryngoscopy and intubation with transdermal buprenorphine patch under general anesthesia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/09/045432
Enrollment
60
Registered
2022-09-12
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: 4- Measurement and Monitoring Health Condition 2: 4- Measurement and Monitoring

Interventions

Intervention1: buprenorphine: buprenorphine patch(10mg) will be applied transdermally once to the patients 12 hours prior to surgery on non-hairy area and will be covered with occlusive dressing by nu

Sponsors

Mahatma Gandhi University Of Medical Sciences And Technology
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patient posted for surgery under general anaesthesia 2. patient with American Society of anaesthesiologists (ASA) Class I and II 3. patient of any sex (male or female) aged between 18-60 years 4. patient who give consent to involve in study

Exclusion criteria

Exclusion criteria: ïâ??·Patient with American Society of Anaesthesiologists (ASA) Class III and IV ïâ??·Patient allergic to buprenorphine ïâ??·Patients with anticipated difficult intubation (Modified mallapatti score 3 or more) 1.More than one attempt at intubation 2.When intubation time exceeds 30 seconds 3.Patients with severe cardiopulmonary compromise 4.Pregnant female 5.Patients with liver and kidney disease 6.Patient refusal

Design outcomes

Primary

MeasureTime frame
to observe any changes in systolic blood pressure after laryngoscopy and intubation.Timepoint: preoperatively and postoperatively—

Secondary

MeasureTime frame
to observe changes in diastolic blood pressure,mean areterial pressure, and ecgTimepoint: preoperatively and intraoperatively—

Countries

India

Contacts

Public ContactPreetika Dhall

Mahatma Gandhi University Of Medical Sciences And Technology

Dr.vipin28@gmail.com8396007347

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026