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Controlled hypotension for Functional Endoscopic Sinus Surgery: a comparison of magnesium sulphate and dexmedetomidine

Controlled hypotension for functional endoscopic sinus surgery a randomized double blinded comparison of magnesium sulphate and dexmedetomidine

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/09/045365
Enrollment
70
Registered
2022-09-09
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H958- Other intraoperative and postprocedural complications and disorders of the ear and mastoid process, not elsewhere classified

Interventions

Intervention1: Dexmedetomidine: Dexmedetomidine 1 microgram/kg body weight diluted in 100 ml of 0.9% normal saline intravenous is administered over 10 minutes as the loading dose. For infusion 100mcg

Sponsors

Shri BM Patil Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA grade 1 and 2

Exclusion criteria

Exclusion criteria: Denial to participate Hypersensitivity to the drugs studied Long term opioid use

Design outcomes

Primary

MeasureTime frame
comparison of the time taken for reaching the target MAP in the two study drugs. group A is given inj Magnesiusm sulphate i/v loading dose 40 mg/kg diluted in 100 ml 0.9% normal saline over a period of 10 mins followed by an iv infusion of 10-15 mg/kg/hr via an infusion pump. group B is given inj Dexmeditomidine iv loading dose of 1mcg/kr diluted in 100 ml 0.9% normal saline over 10 mins followed by an iv infusio n at 0.2-0.7 mcg/kg/hr via an infusion pump.Timepoint: comparison of the time taken for reaching the target MAP in the two study drugs. baseline readings are noted down and later at the time of induction, intubation, at the time of drug administration, 5 mins, 10 mins and 15 mins after drug administration.

Secondary

MeasureTime frame
to compare the number of patients requiring a minimum and maximun infusion doses of study drugs.Timepoint: 1.5 yrs

Countries

India

Contacts

Public ContactNayantara K P

Shri B M Patil Medical College

drvijaykatti@gmail.com9844585900

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026