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Severity of Psoriasis and a few inflammatory markers.

Serum Tumor Necrosis Factor- Alpha and C-Reactive protein levels in psoriasis and correlation with disease severity.

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2022/09/045319
Enrollment
70
Registered
2022-09-07
Start date
Unknown
Completion date
Unknown
Last updated
2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L404- Guttate psoriasis Health Condition 2: L408- Other psoriasis Health Condition 3: L400- Psoriasis vulgaris

Interventions

None listed

Sponsors

VINOLYN DSOUZA
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. All the patients with clinical diagnosis of psoriasis 2. Patients above the age of 12 years willing to participate in the study. 3. Patients who were on systemic treatment and had stopped 60 days prior to the study. 4. All age and sex matched healthy volunteers willing to participate in the study.

Exclusion criteria

Exclusion criteria: 1. Patients with Psoriasis –on systemic drugs like Methotrexate, Cyclosporine, Apremilast and Biologicals for the last 60 days. 2. Patients with a clinical diagnosis of palmoplantar and pustular psoriasis and acute febrile illness. 3. Patients with other pre-existing skin disorders.

Design outcomes

Primary

MeasureTime frame
This study will help to estimate the levels of an inflammatory cytokine (TNF a) and a chronic inflammatory marker (CRP) in psoriasis in an Indian population. This study will also determine whether these levels can be correlated with the disease severity.Timepoint: 18 months

Secondary

MeasureTime frame
The results will suggest the possible role of the markers in the etiopathogenesis and management of the disease.Timepoint: 18 months

Countries

India

Contacts

Public ContactVINOLYN DSOUZA

FATHER MULLER MEDICAL COLLEGE HOSPITAL

rameshderma@gmail.com9845084224

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026