To Compare the effectiveness of platelet concentrate with two different bone graft material for the periodontal defect in human

A clinical and radiographic study to evaluate and compare the effectiveness of Nanocrystalline hydroxyapatite with Advanced Platelet Rich Fibrin(A-PRF)and Hydroxyapatite reinforced Beta tri-calcium phosphate(HA+ß-TCP) with A-PRF in the treatment of human infrabony defects-A cross sectional study.

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/09/045318

Enrollment

Registered

2022-09-07

Start date

Unknown

Completion date

Unknown

Last updated

2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Nanocrystalline hydroxyapatite with Advanced platelet rich fibrin (A- PRF).: Nanocrystalline hydroxyapatite with A-PRF placed in 14 subjects having Infrabony defects . Control Intervent

Eligibility

Inclusion criteria

Inclusion criteria: 1.Systematically healthy patient. 2.Following initial therapy, presence of minimum 1 or 2 interproximal infrabony osseous defect PPD = 5mm and CAL = 5 and which are radiographically noticeable. 3.Clinically and radiographically there should be = 3mm defect depth which is affirmed on intrasurgical measurement. 4.A radiographically determined defect base should be minimum of 3 mm above the apex of the tooth 5.Presence of minimum =2mm zone of keratinized gingiva to permit total soft tissue coverage of the defect area.

Exclusion criteria

Exclusion criteria: 1.Patient diagnosed with aggressive periodontitis. 2.Patients with poor oral hygiene care (Plaque Index >1) 3.Patients using tobacco in any form . 4.Involved tooth with inadequate root canal therapy and subsequent restoration 5.Involved tooth having mobility greater than grade II ,or defect extending in to furcation and third molars . 6.Prior history of periodontal surgery of the selected segment. 7.Females who are pregnant or lactating. 8.There is clinical and radiographic sign of untreated acute infection at the selected site, root fracture,apical pathology ,severe root irregularities, cemental pearls, cementoenamel projections, untreated carious lesion on root surface.

Design outcomes

Primary

Measure	Time frame
Radiographic Bone Fill In Infrabony Defects at 6 Month Post Surgery.Timepoint: Radiographic Bone Fill In Infrabony Defects at 6 Month Post Surgery.	—

Secondary

Measure	Time frame
Gain in Clinical Attachment Level( CAL) Reduction In Probing Pocket Depth (PPD)Timepoint: 6 Months	—

Countries

India

Contacts

Public ContactDr Aishwarya Rathod

Sharad Pawar Dental College, Sawangi.Wardha.

priyanka.banode@gmail.com09960713010

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026