Health Condition 1: E282- Polycystic ovarian syndrome
Conditions
Interventions
Intervention1: PROBIOTIC CAPSULE: PROBIOTIC CAPSULE (lactobacillus
acidophilus, lactobacillus rhamnosus, lactobacillus reuteri,
lactobacillus plantarum, lactobacillus casei, lactobacillus
fermentum, a
Sponsors
JAWAHARLAL INSTITUTE OF POSTGRADUATE MEDICAL EDUCATION AND RESEARCH
Eligibility
Inclusion criteria
Inclusion criteria: Newly diagnosed PCOS women by Rotterdamââ?¬•s criteria with the presence of any two of the following: I) Oligomenorrhea/ dysmenorrhea. II) hyperandrogenism/hyperandrogenemia hirsutism, acne and male pattern baldness III) polycystic ovarian morphology on USG Aged 18 to 45 years, whose testosterone is more than 76ng/dl and are started on standard treatment (Life style modification/metformin / metformin+ OCP / antiandrogen) visiting the outpatient Department of Obstetrics and Gynaecology
Exclusion criteria
Exclusion criteria: 1. Hyperandrogenism due to causes other than polycystic ovarian syndrome such as Cushingââ?¬•s, hyperprolactinemia, adrenal tumors and late onset congenital adrenal hyperplasia. 2. Inflammatory bowel disease and cancers in GIT (carcinoid syndrome) 3. Major surgery in the GIT (colostomy, Whipple procedure) 4. Chronic diseases like thyroid dysfunction, SLE and other autoimmune disorders. 5. Past history of antibiotics usage within a period of last one month. 6. Pregnancy and lactation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| TO look for a decrease in serum total testosterone levelTimepoint: baseline value and after 3 months | — |
Secondary
| Measure | Time frame |
|---|---|
| to look for values like MDA( malondialdehyde), TAC(total antioxidant capacity) and hsCrp(high sensitive C reactive protein)Timepoint: baseline value and after 3 months | — |
Countries
India
Contacts
Public ContactKARTHIK J
JAWAHARLAL INSTITUTE OF POSTGRADUATE MEDICAL EDUCATION AND RESEARCH
Outcome results
None listed