Comparison of Effect of Airway Nebulization with 2% Lignocaine,nebulised 1mcg/kg dexmedetomidine and 0.25%Ropivacaine on Intubation and Extubation Response in Patients Undergoing Surgery under General Anesthesia

Comparison of Effect of Airway Nebulization with lignocaine 2% nebulized Dexmedetomidine and Ropivacaine 0.25% on Intubation and Extubation response in patients undergoing surgery under general Anaesthesia: A Randomized Double Blind clinical trialÃ¢â?¬?

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/09/045292

Enrollment

Registered

2022-09-07

Start date

Unknown

Completion date

Unknown

Last updated

2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: dexmedetomidine: Dexmedetomidine at a dose of 1 Ã?Âµg/kg (mixed with saline to a total volume of 5 ml) nebulisation was administered Control Intervention1: lignocaine: 5 ml of 2% lignoc

Eligibility

Inclusion criteria

Inclusion criteria: Elective surgery under general anesthesia with endotracheal intubation cases

Exclusion criteria

Exclusion criteria: ASA 3 or more Patients with history of risk factors for perioperative aspiration of gastric contents, history of chronic obstructive pulmonary disease, asthma, history of recent respiratory infections, duration of surgery more than 3 h were excluded from the study. Pregnant and lactating mother Anticipated difficult airway

Design outcomes

Primary

Measure	Time frame
attenuation of intubation responseTimepoint: MAP, HR, and SPO2 at; Baseline (T1) Upon tracheal intubation (T2) Upon anesthetic withdrawal (T3) Upon eye opening on verbal commands (T4) Upon tracheal extubation (T5) Two min after extubation (T6).	—

Secondary

Measure	Time frame
extubation responseTimepoint: up on end of surgery	—

Countries

India

Contacts

Public ContactE Lavanya

srilakshmi narayana institute of medical sciences

dr.lavanya08@gmail.com09629181969

Outcome results