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Administration of surfactant by thin catheter (LISA) using video laryngoscope to decrease pain in neonates

Less invasive surfactant administration (LISA) using video laryngoscope to decrease pain in neonates: A randomized controlled trial

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/09/045204
Enrollment
42
Registered
2022-09-05
Start date
Unknown
Completion date
Unknown
Last updated
2024-12-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: P220- Respiratory distress syndrome of newborn

Interventions

Intervention1: Administration of surfactant by LISA technique using video laryngoscope: Surfactant administration by LISA technique will be done using a video laryngoscope by personnel who has either

Sponsors

Mude Praneetha
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Preterm neonates requiring rescue surfactant, i.e., FiO2 requirement > 0.3 on CPAP pressure of at least 6 cm H2O

Exclusion criteria

Exclusion criteria: Neonates who require intubation in the delivery room for stabilization

Design outcomes

Primary

MeasureTime frame
FANS score (Faceless acute neonatal pain scale) will be assessed to evaluate procedural pain in neonates below 35 weeks of gestational age while administering surfactant by LISA technique using any of the two laryngoscopes (video vs. conventional)Timepoint: 1. 5 minutes before procedure (baseline) 2. Immediately post procedure 3. 5 minutes post procedure 4. 10 minutes post procedure

Secondary

MeasureTime frame
Time taken to complete the procedure Timepoint: At the time of procedure;Number of attempts to complete the procedure successfullyTimepoint: At the time of procedure;To record adverse events during the procedureTimepoint: At the time of procedure;Incidence of intraventricular hemorrhageTimepoint: on day 7 of life

Countries

India

Contacts

Public ContactMude Praneetha

All India Institute of Medical Sciences, Bhubaneswar

neonat_tapas@aiimsbhubaneswar.edu.in9438884114

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Aug 27, 2026