Health Condition 1: K800- Calculus of gallbladder with acutecholecystitis
Conditions
Interventions
Intervention1: dexmedetomidine: once the patient consents they will be allocated to a group and inj dexmedetomidine 1.5ug/kg diluted to make a volume of 5 ml ,injected 20 mins prior to surgery then st
Sponsors
Sharda Hospital
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patient scheduled for elective laproscopic cholecystectomy 2. age 18-60 years 3. both genders 4. ASA grade 1 and 2
Exclusion criteria
Exclusion criteria: 1. Patients refusal to participate in study 2. Morbid obesity BMI >30 3. History of sleep apnoea 4. Pharmacological therapy - Benzodiazipines, opoids , antipsychotics 5. anticipated difficult intubation 6. Sinus bradycardia or bundle branch block on ECG 7. Pregnant females 8. coagulopathy or bleeding diathesis 9. history of hypertension , diabetes mellitus, thyroid disease. 10. history of CNS , cardiovascular and renal diesease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the induction dose of propofol , in the three groups , midazolam , dexmedetomidine and the control groupTimepoint: We will monitor Heart Rate, Blood Pressure, Oxygen saturation ,Bispectral Index Value at - Preoperative period Preinduction period Preintubation . At The Time of intubation. Post intubation every minute till 10 minutes then every 10 minute till the end of surgery then we will monitor the outcome with modified Aldrete score post operatively. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. To compare the haemodynamic changes between different groups during intubation. 2. To compare the recovery profile between different groups. 3. To observe the post anaesthetic complications if any.Timepoint: 1 hour | — |
Countries
India
Contacts
Public ContactDr Habiba Atif
School of Medical Sciences and Research ,Sharda University
Outcome results
None listed