Health Condition 1: R799- Abnormal finding of blood chemistry, unspecified
Conditions
Interventions
Control Intervention1: 0.9% saline: Intravenous Fluid used for maintenance and resuscitation(10-20 ml/kg) for first 72 hours.
Control Intervention2: Ringers Lactate: Intravenous Fluid used for mainten
Sponsors
St Stephens Hospital
Eligibility
Inclusion criteria
Inclusion criteria: 1.All patients from 1 month upto 12 years with hypoperfusion admitted in PICU requiring fluid resuscitation and maintenance fluid. 2.Patients who will receive fluid boluses in emergency, pediatric ward, post ICU and thereafter shifted to PICU.
Exclusion criteria
Exclusion criteria: All the patients 1.With head injury. 2.chronic kidney disease with hyperkalemia With Burns 3.Children already on maintenance fluid requiring resuscitation. 4.whose parents refused consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| a.Acid base imbalance and occurrence of hyperchloremia.- pH and base excess will be measured. Normal pH range will be taken as 7.35-7.45 and normal base excess for infants will be -7 to -1, for children it will be -4 to +2. Normal serum chloride levels as per lab of the study hospital. b.Sodium and potassium disturbance – Hypernatremia is defined by serum sodium concentration more than 145meq/l and hyponatremia by serum sodium concentration 135meq/l. Timepoint: At baseline, 12 hours, 24 hours thereafter as when required till 72 hours | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Incidence of Acute kidney injury- Acute kidney injury is defined by KDIGO criteria 2.Coagulopathy- PT, APTT, INR will be measured and assessed by standard lab values. 3.Duration of PICU and hospital stay: will be calculated in days. Timepoint: At admission, at 12 hours,24 hours | — |
Countries
India
Contacts
Public ContactDr Yatnesh More
St Stephens Hospital
Outcome results
None listed