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Comparison of phenylephrine and norepinephrine for treatment of maternal hypotension

Intravenous bolus dose of phenylephrine and intravenous bolus dose of norepinephrine for treatment of maternal hypotension in spinal anasthesia during Caesarean section-A comparative study - IPNMSC

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/09/045141
Enrollment
72
Registered
2022-09-01
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O80-O82- Encounter for delivery

Interventions

Intervention1: Administration of intravenous phenylepinephrine: 50 microgram phenylepinephrine given intravenously when blood pressure of patient falls below 20% of baseline value Control Intervention

Sponsors

Danish Jamal ansari
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: (1)ASA 2. (2)Singleton pregnancy. (3)Scheduled for elective Caesarean section under spinal anaesthesia

Exclusion criteria

Exclusion criteria: Age less than 18 year or more than 45 year. ââ??ª Height less than 150 cm or more than 180 cm. ââ??ª Weight less than 50 kg or more than 100 kg, ââ??ª Contraindications to spinal anaesthesia, ââ??ª Allergy to drugs used in the study. ââ??ª Patient with preeclampsia, placenta praevia, diabetes mellitus, hypertension, or cardiovascular disease. ââ??ª Non willing patents.

Design outcomes

Primary

MeasureTime frame
ââ??ª To estimate the efficacy and safety of norepinephrine and phenylephrine for treatment of maternal hypotension(post spinal)during Caesarean section.Timepoint: ââ??ª during Caesarean section—

Secondary

MeasureTime frame
To compare the hemodynamics of norepinephrine and phenylephrine treated patients during Caesarean section. ââ??ª To compare neonatal APGAR score between the two vasopressor. Timepoint: To compare the hemodynamics of norepinephrine and phenylephrine treated patients during Caesarean section. ââ??ª To compare neonatal APGAR score between the two vasopressor.—

Countries

India

Contacts

Public ContactDr Danish Jamal Ansari

KING GEORGE�S MEDICAL UNIVERSITY, UP, LUCKNOW

dineshkaushal91@yahoo.com9839089242

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026