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"Surveillance of Carbapenem Resistant Enterobacterales in two intensive care units in India

Carbapenem Resistant Enterobacterales Surveillance in Two Intensive Care Units in India (CRESCENT Study) - CRESCENT

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/08/045131
Enrollment
300
Registered
2022-08-31
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: A09- Infectious gastroenteritis and colitis, unspecified Health Condition 2: A415- Sepsis due to other Gram-negativeorganisms

Interventions

Intervention1: IPC based intervention: The baseline data collected on CRE rate ratios and prevalence would be assessed to design and formulate an IPC based intervention Intervention2: Infection Preven

Sponsors

Washington University School of Medicine
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Consenting patients admitted to selected ICUs

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Estimates of admission CRE prevalence and CRE acquisition rates in the study ICUs using SCS.Timepoint: At 24-48 hours of ICU admission, every week, at ICU discharge or death or until colonized with CRE

Secondary

MeasureTime frame
2. Risk factors associated with CRE colonization on admission and CRE acquisition during ICU stay. 3. Estimates of CRE prevalence detected by routine clinical cultures versus surveillance cultures. 4. Estimates of admission and discharge CRE rate ratios in the ICUs using LCS strategy that are comparable to SCS strategy. 5. Clinical risk factor and clinical culture information role in augmenting the LCS strategy. 6. Baseline infection prevention practices in study ICUs focusing on environmental cleaning practices of immediate patient environment, hand hygiene practice and contact isolation precaution practices for CRE positive patients. 7. CRE incidence rate ratios using the optimal LCS strategy before and after the infection prevention intervention Timepoint: 3,4,7 : At 24-48 hours of ICU admission, every week, at ICU discharge or death or until colonized with CRE 2,5,6 : derived post data collection and analysis

Countries

India

Contacts

Public ContactSanjeev Singh

Amrita Institute of Medical Sciences

sanjeevksingh@aims.amrita.edu

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026