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A clinical study to evaluate the efficiency of two drugs to stop bleeding after wisdom tooth removal

Comparative Evaluation of Efficacy of Chitosan vs Gelfoam as a Hemostatic Agent After Surgical Removal of Impacted Mandibular Third Molars: A Double Blinded Randomized Controlled Study

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/08/045102
Enrollment
68
Registered
2022-08-30
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K011- Impacted teeth

Interventions

Intervention1: Chitosan: Non absorbable chitosan pellet put in the post extraction socket and removal in 15 mins Control Intervention1: Gelfoam: Absorbable gelfoam pellet put in the post extraction so

Sponsors

Self Dr Parvaket Patel
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients indicated for surgical extraction of impacted mandibular third molars 2.Patients willing to participate in the study 3.Patients undergoing oral anticoagulative therapy requiring surgical extraction of mandibular third molars 4.Patients without any history of chronic illness

Exclusion criteria

Exclusion criteria: 1.Patients who are allergic to shellfish 2.Patients who are allergic to gelatin/gelatin-based products 3.Patients presenting in a hypercoagulable state 4.Patients with renal dysfunction, liver disorders, asthma, pregnancy. 5.Patients allergic to Chitosan/ Chitin and its byproducts. 6.Patients with an intellectual deficit

Design outcomes

Primary

MeasureTime frame
Hemostasis and wound healing to be assessed post operativelyTimepoint: surgical wound will be assessed on day of surgery, and post operatively after 3 days and 7 days respectively

Secondary

MeasureTime frame
Healing by Landry healing indexTimepoint: post operative day 7;Healing measured by Landry Healing IndexTimepoint: post operative day 3;Post-operative pain by Visual Analogue scaleTimepoint: post operative day 3 and day 7

Countries

India

Contacts

Public ContactDr Parvaket Patel

Nair Hospital Dental College

drnnandrade@gmail.com9821126837

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026