Health Condition 1: E119- Type 2 diabetes mellitus without complications
Conditions
Interventions
Intervention1: Exercise with nutrition (prebiotic, probiotic and protein) arm: Exercise with protein and synbiotic (combination of prebiotic and probiotic) supplement for 12 weeks
Intervention2: Exerc
Sponsors
St Johns Research Institute
Eligibility
Inclusion criteria
Inclusion criteria: 40-70 years Both male and female BMI 18.5-30 kg/m2 HbA1c = 5.7% or FBS = 100 mg/dl or PPBS = 140 mg/dl Diabetes within 5 years of diagnosis
Exclusion criteria
Exclusion criteria: Type 1 diabetes or type 2 diabetes with complications (diabetic foot, frequent hypoglycemic episodes) Current or prior history of inflammatory bowel disease, bariatric surgery, irritable bowel syndrome or any other malabsorption disorder Current history of cancer or in remission for History of active cardiovascular disease with surgical intervention, hepatic or renal insufficiency, severe anemia or tuberculosis. Current or recent antibiotic or corticosteroid use ( Current use of probiotic or prebiotic or protein supplementation Known allergy or intolerance to probiotic or prebiotic or protein Any neuropathy or neuromuscular disorder affecting movement Any form of recent joint injuries (knee and wrist) History of severe form of osteoarthritis affecting movement
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Glycemic status and quality of lifeTimepoint: At baseline and at 12 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| Physical function (muscle strength, muscle endurance, body composition, and exercise capacity) and mental well-being (stress, anxiety, depression and cognitive function)Timepoint: At baseline and at 12 weeks;Gut bacterial composition, gut function marker and inflammatory markersTimepoint: At baseline and at 12 weeks | — |
Countries
India
Contacts
Public ContactSHINJINI BHATTACHARYA
St Johns Medical College
Outcome results
None listed