Health Condition 1: - Health Condition 2: J99- Respiratory disorders in diseasesclassified elsewhere
Conditions
Interventions
None listed
Sponsors
MAHE Manipal
Eligibility
Inclusion criteria
Inclusion criteria: Patients being planned for definitive or adjuvant thoracic radiotherapy that involves direct radiation exposure to at least a part of heart and lungs. 2. Good performance score (KPS >=70), and ability to perform the physical tests required for assessment. 3. Adequate baseline hematocrit, and cardiac and pulmonary function. Estimated life expectancy of at least 12 months. 4. Willing to participate in the study, and provides voluntary informed consent
Exclusion criteria
Exclusion criteria: 1. KPS 2. Patients being treated with extreme hypofractionated regimen, mainly SBRT. 3. Other comorbidities such as Chronic Lung disease, cardiac disease, anemia at presentation, chronic kidney disease, peripheral neuropathy, disabilities in ambulation, etc., that might interfere with the conduct of the physical assessments. 4. Baseline impairment in respiratory or cardiac function as an indirect result of the tumor; eg. Lobar/pulmonary collapse secondary to obstructing tumor, pleural or pericardial effusion, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.Correlation between lung and heart dose exposure and fall in effort tolerance: a. Correlation coefficient. b. Regression graph. c. 6-minute walk distance. Timepoint: 4years | — |
Secondary
| Measure | Time frame |
|---|---|
| 2. Effect of thoracic radiotherapy on effort toleranceTimepoint: 4years | — |
Countries
India
Contacts
Public Contactjyothi
Kasturba Medical College MAHE ,Manipal
Outcome results
None listed