Health Condition 1: O140- Mild to moderate pre-eclampsia
Conditions
Interventions
Intervention1: Injection Noradrenaline
Bitartrate: Injection Noradrenaline
Bitartrate,intravenous,as 5
micrograms per ml.1ml of the
drug given as boluses to treat
each systolic blood pressure
reading
Sponsors
Dr Trina Sen
Dr Prerona Saha
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients willing to participate in the study 2.American Society of Anaesthesiologists physical status 2 3.Women with singleton pregnancy scheduled for elective caesarean section under spinal anaesthesia, with preeclampsia 4.Women aged 18years and more
Exclusion criteria
Exclusion criteria: 1.Women not developing post-spinal hypotension(defined as 20% or more decline in sysytolic arterial pressure from baseline value or absolute value of less than 100 mm Hg) 2.Women with other medical conditions(diabetes,cardiovascular diseases,cerebrovascular diseases,renal impairment) 3.Patients having placenta praevia 4.Parturients with fetal malformations 5.On prolonged drug therapy like monoamine oxidase inhibitors,tricyclic anti-depressants 6.suspected fetal compromise
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the effect of bolus doses of phenylephrine and noradrenaline on umbilical cord blood pH in preeclampsia patientsTimepoint: At the delivery of baby before the first cry | — |
Secondary
| Measure | Time frame |
|---|---|
| APGAR score of the babyTimepoint: at 1minute and 5minutes;Changes in maternal heart rate,systolic arterial pressure and mean arterial pressureTimepoint: After subarachnoid block every 3minutes till the delivery of baby;Incidence of maternal complications-Nausea,vomiting,chest discomfortTimepoint: from administration of drug till the end of surgery | — |
Countries
India
Contacts
Public ContactDr Trina Sen
Gauhati Medical College and Hospital
Outcome results
None listed