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A study to know if destruction (radiofrequency ablation) of nerves causing pain in the knee before surgery leads to better post-operative outcome following knee replacement surgery

Comparison of preoperative genicular nerve radiofrequency ablation with conventional analgesics on post-operative outcome following total knee arthroplasty: A randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/08/044927
Enrollment
42
Registered
2022-08-25
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M179- Osteoarthritis of knee, unspecified

Interventions

Intervention1: Radiofrequency ablation of genicular nerves: Genicular nerve radio frequency ablation will be done at least 4 weeks prior to total knee replacement surgery. Control Intervention1: The p

Sponsors

AIIMS Jodhpur
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Following written consent, all patients, aged above 50 years, ASA Iââ?¬â??II, undergoing elective TKR will be enrolled.

Exclusion criteria

Exclusion criteria: Patients with coagulation disorders, cognitive impairment or communication disorders, and concurrent treatment with analgesics for other indications will be excluded from the study.

Design outcomes

Primary

MeasureTime frame
The primary outcome measure will be level of physical activity using Lysholm Score (LS)Timepoint: Measurements will be taken at 4 time points- 1) baseline (On day of first hospital OPD visit), 2) 4 weeks before surgery, 3) on the day of surgery and 4) at follow-up 3 months post-surgery.

Secondary

MeasureTime frame
Secondary objectives are to determine effect on knee range of motion (ROM), Tegner Activity Scale (TAS), Stair Climbing Test (SCT), patient�s perception using the subjective Patients� Global Impression of Change (PGIC) scale, total analgesic consumption, number of PT sessions attended and level of comfort during PT sessions(Likert scale)Timepoint: Measurements will be taken at 4-time points- 1) baseline (On the day of the first hospital OPD visit), 2) 4 weeks before surgery, 3) on the day of surgery and 4) at follow-up 3 months post-surgery.

Countries

India

Contacts

Public ContactDr Bharat Paliwal

All India Institute of Medical Sciences Jodhpur

docbpali@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026