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Bacterial growth and susceptibility pattern of antibiotics in Subglottic versus Endotracheal Secretion in patients with Ventilator-associated Pneumonia

Bacterial Colonization and Antimicrobial susceptibilty pattern of Subglottic versus Endotracheal Secretion in patients with Ventilator associated Pneumonia: A Diagnostic Accuracy Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2022/08/044892
Enrollment
175
Registered
2022-08-24
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J189- Pneumonia, unspecified organism

Interventions

Intervention1: Collection of Endotracheal Aspirate: On onset on clinical VAP,Endotracheal Aspirate samples will be collected in mucous extractor, adequately labelled and immediately transported to lab

Sponsors

None
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Age >18 years of age, invasive mechanical ventilation for at least 48 hours and new onset Clinically defined VAP

Exclusion criteria

Exclusion criteria: 1. Pre-existing Healthcare associated pneumonia within last 90 days 2. Community acquired pneumonia 3. Pregnancy 4. Organ transplant 5. Any immunocompromised state

Design outcomes

Primary

MeasureTime frame
To estimate the diagnostic accuracy of antibiotic-sensitivity profile of bacterial isolates identified within SGA culture versus convergent ETA culture isolates in patients with clinically defined VAP undergoing IMVTimepoint: At onset of clinical VAP

Secondary

MeasureTime frame
To analyse the clinical outcome parameters with respect to culture sensitivity report.Timepoint: 28 days post inclusion, discharge or death whichever occurs earlier;To identify convergence and accuracy within microbiological flora of ETA versus SGA sample of patients undergoing IMV with clinically defined VAP.Timepoint: At onset of clinical VAP

Countries

India

Contacts

Public ContactDr Gaurav Jain

AIIMS Rishikesh

gauravhld@gmail.com8808631209

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026