Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: nil: nil
Control Intervention1: nil: nil
Sponsors
AIIMS
Eligibility
Inclusion criteria
Inclusion criteria: 1.Age above 60 years 2.Undergoing surgery of duration from 1-3 hours 3.Can give informed consent themselves
Exclusion criteria
Exclusion criteria: 1.Significant kidney disease (stage 4 kidney disease or higher). 2.Significant liver disease (Child-Pugh B or C class). 3.Allergic to neostigmine or sugammadex. 4.History of a neuromuscular disorder. 5.History of chronic obstructive pulmonary disease. 6.Pregnancy or nursing women. 7.Refusal to participate. 8.Arrhythmic disease or taking anti-arrhythmic drugs. 9.Inability to extubate at the end of surgery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the ratio of the handgrip strength at TOF count of 0.9 to the TFIO at baselineTimepoint: 60 MINUTES | — |
Secondary
| Measure | Time frame |
|---|---|
| (1) the ratio of the handgrip strength, parasternal intercostal muscle, diaphragm excursion at the time of TOF 0.9, cTOFr 0.9 and 30 min after PACU admission to baseline, respectively; ( 2) the recovery time from TOFr 0.9 to TOFr 0.95 and to unity, respectively. Timepoint: from pre induction to 30 minutes after surgery | — |
Countries
India
Contacts
Public ContactPuneet Khanna
AIIMS, New Delhi
Outcome results
None listed