Health Condition 1: T31- Burns classified according to extent of body surface involved Health Condition 2: O- Medical and Surgical
Conditions
Interventions
Intervention1: Group KD: Group KD - Patients will receive KETODEX (Ketamine with dexmedetomidine), 0.5 µg/kg dexmedetomidine given as bolus over 5 min with ketamine 1mg/kg in the 5th minute. This will
Sponsors
AIIMS
Eligibility
Inclusion criteria
Inclusion criteria: All ASA 1-2 patients aged >18 years with burn injury having superficial to partial thickness burns scheduled for burn dressing.
Exclusion criteria
Exclusion criteria: a) Patients with any serious co-morbidities like cardiovascular disease, cerebrovascular disease , intracranial hypertension and respiratory tract infection b) Sinus bradycardia c) Deep burns or >50% burns d) History of substance abuse or dependence like alcohol e) Patients requiring mechanical ventilation f) Patients requiring vasopressor support g) Patients in the initial resuscitation phase h) Difficult airway i) History of serious adverse effects related to anaesthesia drugs like allergy j) Pregnancy k) History of seizures l) History of any neuropsychiatric disorder m) Patients on study drug infusion in last 12 hours
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the sedative and analgesic effects of Ketofol, Ketodex and Ketofen for dressing in burn patients by evaluating 1.NRS pain scores 2.Ramsay sedation score Timepoint: at the time of dressing | — |
Secondary
| Measure | Time frame |
|---|---|
| To evaluate the effect of Ketofol , Ketodex and Ketofen on 1. Hemodynamic profile (HR ,SBP , DBP ,MAP, Spo2, RR) 2. Satisfaction of the patient 3. Ease of dressing 4. Any adverse effects Timepoint: at the time of dressing | — |
Countries
India
Contacts
Public ContactShailendra Kumar
AIIMS, New Delhi
Outcome results
None listed