Health Condition 1: C148- Malignant neoplasm of overlappingsites of lip, oral cavity and pharynx
Conditions
Interventions
None listed
Sponsors
Rajiv Gandhi University of Health Sciences
Eligibility
Inclusion criteria
Inclusion criteria: The study consists of 2 groups within the age range of 20 to 60 years. Group A: 26 subjects of Oral Potentially Malignant Disorders Group B: 26 subjects of healthy controls Patients will be informed about the study and consent will be obtained. The subjects will be collected by Simple random sampling method. Subjects will be diagnosed clinically and confirmed histopathologically as oral potentially malignant disorders will be considered as cases.
Exclusion criteria
Exclusion criteria: Patients with history of Renal diseases, hematological disorders, liver diseases, gastrointestinal disorders, nutritional deficiencies, prior medication of external supplements and pregnancy will be excluded from the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To obtain a reliable biomarker Serum Methyl Malonic Acid in Oral Potentially Malignant Disorders and to coorelate the marker with serum Vitamin B12 and the stages of progression of the Oral Potentially Malignant disorderTimepoint: To obtain a reliable biomarker Serum Methyl Malonic Acid in Oral Potentially Malignant Disorders in first 6 months and to coorelate the marker with serum Vitamin B12 and the stages of progression of the Oral Potentially Malignant disorder in the next 6 months. | — |
Secondary
| Measure | Time frame |
|---|---|
| The levels of METHYL Malonic Acid may vary in different stages of Oral Potentially Malignant Disorders and in different lesionsTimepoint: 2 years | — |
Countries
India
Contacts
Public ContactDurga Rajaram Okade
Sri Rajiv Gandhi College of Dental Sciences and hospital
Outcome results
None listed