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TO assess the effect of vibration and low level laser therapy on the amount of IL1- Beta, IL-8 and orthodontic tooth movement

To evaluate the effect of vibratory stimulation and low level laser therapy on the levels of Interlukin-1 Beta, Interlukin-8 and amount of Tooth Movement

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/08/044842
Enrollment
30
Registered
2022-08-23
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Laser Irradiation, Vibratory stimulation: Lasers and vibrations are used normally in orthodontia to increase the rate of tooth movement, this falls under the rapid acceleratory phenomen

Sponsors

Dr Aastha Purohit
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Healthy Individuals with no systemic illness requiring maxillary first premolar extraction. Good oral hygiene and periodontal health. No developmental anomaly. No history of previous orthodontic treatment.

Exclusion criteria

Exclusion criteria: History of trauma. Patients with systemic illnesses Taking medications that interfere with orthodontic tooth movement Patients with parafunctional habits Severely periodontally compromised. Periapical inflammation of cysts/ tumors.

Design outcomes

Primary

MeasureTime frame
The efficacy of high frequency vibrations combined with low level laser therapy is expected to be higher than low level laser therapy which is higher than control group which is not receiving any laser or vibration therapy on the levels of Interleukin-1 beta and Interleukin-8 in Gingival Crevicular Fluid.Timepoint: 3 months

Secondary

MeasureTime frame
Group receiving high frequency vibrations combined with low level laser therapy is expected to increase orthodontic tooth movement most followed by group receiving only low level laser therapy followed by control group which is not receiving any laser or vibration therapyTimepoint: 3 months

Countries

India

Contacts

Public ContactDr Aastha Purohit

Inderprastha Dental College and Hospital, Uttar Pradesh

aastha1994purohit@gmail.com09454889318

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026