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Comparison of Intravenous Phenylephrine and Noradrenaline in management of Spinal Anaesthesia Induced Hypotension in Elective Cesarean Section

Two arm Observational Study between Phenylephrine and Noradrenaline in management of Spinal Anaesthesia Induced Hypotension in Elective Cesarean Section

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/08/044815
Enrollment
102
Registered
2022-08-23
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: 1- Obstetrics

Interventions

Control Intervention1: Noradrenaline: Noradrenaline is both alpha1 and beta 1 agonist cause vesoconstriction with minimum or no change in heart rate. Route of administration - intravenous Dose- 4 mic

Sponsors

RGKar Medical College and Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. ASAI II 2. Patients aged 18 and above . 3. Patients undergoing elective and emergency caesarean section under spinal anaesthesia 4. Patients showing hypotension after spinal anaesthesia

Exclusion criteria

Exclusion criteria: 1. ASA III, IV 2. Any spine abnormalities 3. Patient refusal 4. Patient with bleeding disorder 5. Patient in active labour 6. GDM,PIH 7. Height 180cm 8. Allergy in drug use in thesis. 9. Eclampsia and severely preeclampsia 10. Uncontrolled diabetes 11. Patients with coagulopathy secondary to antiblastic cancer therapy 12. Cardiac or neurological diseases 13. Known allergy to the anaesthetic drugs used 14. Bowl obstruction 15. Systemic sepsis 16. Failed/patchy block will be converted into General Anaesthesia and will not be included in the study

Design outcomes

Primary

MeasureTime frame
To compare the effectiveness between Phenylephrine and Noradrenaline via intravenous route in preventing spinal anaesthesia induced hypotension in elective LUCSTimepoint: 6 month after approval of ethical committee

Secondary

MeasureTime frame
To observe any side effectof the drug eg.- bradycardia, tachycardiaTimepoint: 6 month after approval of ethics committee

Countries

India

Contacts

Public ContactDr Arpita Choudhury

R.G.Kar Medical College and Hospital

dr.sankar.roy2010@gmail.com9434165426

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026