Comparative study of use of intravenous bolus dose of mephentermine with norepinephrine in management of spinal anesthesia induced hypotension in lower segment caesarean section surgeries

Comparative study of use of intravenous bolus dose of mephentermine with two different doses of norepinephrine in management of hypotension in lower segment caesarean section surgeries done under sub arachnoid block anaesthesia

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/08/044813

Enrollment

Registered

2022-08-23

Start date

Unknown

Completion date

Unknown

Last updated

2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O94- Sequelae of complication of pregnancy, childbirth, and the puerperium

Interventions

Intervention1: IV norepinephrine: after development of hypotension IV norepinephrine 5 mcg is given every 3 minutes till blood pressure is normalised Intervention2: IV norepinephrine: after developmen

Eligibility

Inclusion criteria

Inclusion criteria: pregnant females of ASA I & II

Exclusion criteria

Exclusion criteria: Patient refusal age > 35 years ASA III & IV

Design outcomes

Primary

Measure	Time frame
number of boluses required to recover from hypotensionTimepoint: number of boluses required to recover from hypotension recorded at 3 mins interval from baseline till stable blood pressure reached	—

Secondary

Measure	Time frame
comparison of hemodynamic parametersTimepoint: 2-4 hours intraoperative period	—

Countries

India

Contacts

Public ContactDr Shikha Sachan

Institute of Medical Sciences, Banaras Hindu University

atulksingh84@gmail.com8317010317

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026