study on role of anti depression activity of ayurvedic medicines

Comparative Evaluation of Anti-Depressant Activity of Mansyadi Capsule Vs Jyotishmati Capsule on Vishaad (Major Depressive Disorder)

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/08/044774

Enrollment

Registered

2022-08-22

Start date

Unknown

Completion date

Unknown

Last updated

2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: F331- Major depressive disorder, recurrent, moderate Health Condition 2: F331- Major depressive disorder, recurrent, moderate

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: 1. Males or females between the age of 30 to 55 years. 2. Subjects who will fulfill the DSM-V criteria for the diagnosis of major depressive disorder without psychotic features and with single or recurrent episode for minimum two weeks. 3. Subjects who will be diagnosed as mild to moderate cases of MDD on Hamilton Depression Rating Scale. 4. Patients willing to give informed consent. 5. Females willing to follow methods of contraception during the course of trial.

Exclusion criteria

Exclusion criteria: 1. Individuals at significant risk of suicide on the basis of the clinical judgement. 2. Pregnant, breast Ã¢â?¬â??feeding or planning to become pregnant during the study. 3. Current history of illness with hepatic, renal, gastroenterological, respiratory, cardiovascular (including IHD), endocrinologic, neurologic, immunologic or hematological diseases and infectious diseases etc. 4. Significantly abnormal laboratory test and finding of electrocardiograph. 5. Current use of drug abuse or alcohol dependence. 6. Diagnosis of panic disorder, generalized anxiety, dementia, bipolar disorder, schizophrenia, or any other psychiatric disorders.

Design outcomes

Primary

Measure	Time frame
Ã¢â?¬Â¢ To study the efficacy of Mansyadi Capsule on Vishaada (Major Depressive Disorder) Ã¢â?¬Â¢ To study the efficacy of Jyotishmati Capsule on Vishaada (Major Depressive Disorder) Ã¢â?¬Â¢ To compare the efficacy of Mansyadi Capsule with Jyotishmati Capsule on Vishaada (Major Depressive Disorder) Timepoint: assessment will be reported on baseline, 30th day, 60th day & 90th day on the basis of Hamilton Depression Rating Scale & Serum Cortisol morning 8 am sample on 0th day & 90th day	—

Measure

Time frame

Ã¢â?¬Â¢ To study the efficacy of Mansyadi Capsule on Vishaada (Major Depressive Disorder) Ã¢â?¬Â¢ To study the efficacy of Jyotishmati Capsule on Vishaada (Major Depressive Disorder) Ã¢â?¬Â¢ To compare the efficacy of Mansyadi Capsule with Jyotishmati Capsule on Vishaada (Major Depressive Disorder) Timepoint: assessment will be reported on baseline, 30th day, 60th day & 90th day on the basis of Hamilton Depression Rating Scale & Serum Cortisol morning 8 am sample on 0th day & 90th day

—

Secondary

Measure	Time frame
no any secondary outcome NILTimepoint: nil	—

Countries

India

Contacts

Public ContactDr Vinod Ade

Mahatma Gandhi Ayurveda College, Salod Wardha

dr.vinodade@gmail.com9689365368

Outcome results