Health Condition 1: E101- Type 1 diabetes mellitus with ketoacidosis
Conditions
Interventions
Intervention1: SC INSULIN: In addition to IV Regular insulin in the standard arm, patients receive an addition dose of insulin in the form NPH Insulin at a dose of 0.25 units/kg split into two doses 1
Sponsors
Jawaharlal Institute of Postgraduate Medical Education and Research
Eligibility
Inclusion criteria
Inclusion criteria: All adults > 18 years of age with DKA. DKA is defined as a patients having all of the following RBS >250mg/dl pH Urine ketones ++(dipstick) Bicarbonates 10
Exclusion criteria
Exclusion criteria: 1.Chronic Liver Disease 2.Chronic Kidney Disease 3.Patient on Assisted mechanical ventilation 4.Hypotensive patients on inotropic support
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Resolution of DKATimepoint: RBS every 2-3 hours VBG every 4-6 hours Till resolution of DKA Patient is assessed every 4-6 hourly till DKA resolves | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess the duration of hospital stay in study participants.Timepoint: At the time of discharge;To determine the frequency of hypoglycemia in study participants.Timepoint: Till the Resolution of DKA;To evaluate the time to rebound hyperglycemia within 24 hours of stopping IV Insulin Infusion.Timepoint: Within 1 day of stopping insulin infusion | — |
Countries
India
Contacts
Public ContactNaveen Baby
Jawaharlal Institute of Postgraduate Medical Education & Research
Outcome results
None listed