Anti-inflammatory and healing potential of Mimosa pudica root extract as an root canal medicament in teeth with periapical infection

Evaluation of anti-inflammatory and healing potential of Mimosa pudica root extract as an intracanal medicament in teeth with periapical lesions Ã¢â?¬â?? An Observational study

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/08/044719

Enrollment

Registered

2022-08-17

Start date

Unknown

Completion date

Unknown

Last updated

2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K049- Other and unspecified diseases ofpulp and periapical tissues

Interventions

Intervention1: Mimosa pudica: Intracanal for 14 days Control Intervention1: Calcium Hydroxide: Intracanal for 14 days

Eligibility

Inclusion criteria

Inclusion criteria: 1. Healthy patients aged between 14 - 50 years. 2. Patients under ASA I & II category. 3. Patients diagnosed with periapical lesion size greater than 2 mm based on PAI score 3, 4 and 5 preoperatively. 4. Teeth with adequate coronal tooth structure for post endodontic restoration.

Exclusion criteria

Exclusion criteria: 1. Patients above ASA III category. 2. Patients who are allergic to drugs. 3. Pregnant and lactating women. 4. Teeth with cracks, vertical root fracture. 5. Periodontally weakened teeth. 6. Retreatment cases. 7. Calcified root canal.

Design outcomes

Primary

Measure	Time frame
Anti inflammatory effect of mimosine root extract on periapical lesionTimepoint: 3,6, and 9 months	—

Secondary

Measure	Time frame
n/aTimepoint: n/a	—

Countries

India

Contacts

Public ContactDr Vijay Amirtharaj L

SRM Institute of Science and Technology

reasearchmaha@gmail.com9381018598

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026