Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Fentanyl and 0.5% hyperbaric bupivacaine: 16mg of 0.5% hyperbaric bupivacaine + 25microgram fentanyl. Intrathecal route, single administration
Intervention2: Dexmedetomidine and 0.5% hy
Sponsors
IVY hospital mohali
Eligibility
Inclusion criteria
Inclusion criteria: ASA grade I and II posted for total knee arthroplasty under spinal anaesthesia
Exclusion criteria
Exclusion criteria: 1. ASA grade III and IV with severe systemic illness 2. Pregnancy 3. Patient with history of heart conduction abnormalities 4. Patient on alpha blockers 5. Any known hypersensitivity to the study drugs 6. Any contraindications to SA such as local infection, coagulopathy. 7. Patient with neurologic disorders
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| duration and quality of sensory-motor block in spinal anaesthesia and duration of postoperative analgesiaTimepoint: duration of motor anaesthesia (time taken to reach Bromage 0 from Bromage III after administration of subarachnoid block) and time of first rescue analgesia (the first time patient complains of pain at surgical site after administration of subarachnoid block) | — |
Secondary
| Measure | Time frame |
|---|---|
| Effect on hemodynamics plus any intraoperative and/or postoperative complications Timepoint: throughout the intraoperative period, at baseline, 0 min, 2, 4, 6, 8, 10, 15, 20, 25, 30, 45, 60, 90, 120, 150, 180 mins after administration of subarachnoid block | — |
Countries
India
Contacts
Public ContactDr Tanya Jindal
Department of anaesthesia and critical care, first floor, IVY hospital Mohali
Outcome results
None listed