Health Condition 1: K801- Calculus of gallbladder with othercholecystitis
Conditions
Interventions
Intervention1: Magnesium sulphate: Administered at a dose of 0.5ml/kg of 10% magnesium sulphate (50mg/kg) over 2-3 mins to be completed 5 minutes before induction
Control Intervention1: Dexmedetomidin
Sponsors
Bankura Sammilani Medical College
Eligibility
Inclusion criteria
Inclusion criteria: Patients belonging to ASA Grade I and ASA Grade II and posted for laparoscopic cholecystectomy.
Exclusion criteria
Exclusion criteria: Patients not willing to give consent, with anticipated difficult airway, history of known allergy to study drug, with labile blood pressure, severe renal disease, endocrine and cardiac dysfunction, patients on drugs like beta-blockers that has drug interaction with study drugs, patients with Lambert Eaton syndrome and myasthenia Gravis, patients with history of chronic alcoholism or drug abuse, patients who are pregnant or lactating mothers are excluded from study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| When both magnesium sulphate and dexmedetomidine will be used at the same moment of anaesthesia in the proposed study one drug is expected to come out with superior efficacy than the other in attenuating haemodynamic changes associated with laparoscopic cholecystectomy.Timepoint: 1hour to 2hours (duration of the particular surgery) | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess the changes in heart rate and blood pressure during endotracheal intubation and endotracheal intubation.Timepoint: 10mins | — |
Countries
India
Contacts
Public ContactDr Swarup Dutta
Bankura Sammilani Medical College
Outcome results
None listed