Comparison of 0.75% Ropivacaine heavy and 0.5% Bupivacaine heavy in spinal anaesthesia for caesarean delivery

Randomised double blinded prospective study to compare the effects of 0.75% Ropivacaine heavy and 0.5% Bupivacaine heavy in subarachnoid block for caesarean delivery in obstetric patients

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/08/044691

Enrollment

120

Registered

2022-08-16

Start date

Unknown

Completion date

Unknown

Last updated

2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O80- Encounter for full-term uncomplicated delivery

Interventions

Intervention1: 0.75% Ropivacaine heavy will be used instead of the routinely used 0.5% Bupivacaine heavy: Hyperbaric Ropivacaine 0.75% 2 ml intrathecally single shot will be used intrathecally for sub

Eligibility

Inclusion criteria

Inclusion criteria: Obstetric patients coming for elective caesarean section Age group of 20-40 years ASA 1 & ASA 2 patients Full term pregnant patients Patients with Single live intrauterine fetus

Exclusion criteria

Exclusion criteria: 1.Patients who refuse 2.Emergency surgeries 3.Age group 40 years of age 4.ASA 3 & ASA 4 patients 5.Pre term patients 6.Multiple pregnancy (twin or more gestation) 7.Associated comorbid conditions( PIH, GDM, Anaemia, Heart disease) 8.Bleeding diathesis patients 9.Fetal indication for caesarean delivery

Design outcomes

Primary

Measure	Time frame
To compare the onset of sensory and motor block, duration of block with 0.75% ropivacaine and 0.5% bupivacaine in spinal anaesthesia for caesarean section.Timepoint: Every 5 minutes for 30 minutes and next 2 hours for regression	—

Secondary

Measure	Time frame
To estimate the differences in hemodynamic variables ( BP, HR) and time for regression of sensory and motor block (assessed by modified Bromage scale) among both the groups.Timepoint: 2hours	—

Countries

India

Contacts

Public ContactChandrakala

Coimbatore medical College

dr.sathya83@gmail.com09578887200

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026