A Study To Compare Two Drugs Namely CARBETOCIN VS OXYTOCIN To Prevent Postpartum Hemorrhage

A COMPARATIVE STUDY OF CARBETOCIN VS OXYTOCIN IN ACTIVE MANAGEMENT OF THIRD STAGE OF LABOR

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/08/044673

Enrollment

190

Registered

2022-08-05

Start date

Unknown

Completion date

Unknown

Last updated

2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O80- Encounter for full-term uncomplicated delivery Health Condition 2: O679- Intrapartum hemorrhage, unspecified

Interventions

Intervention1: WE WILL INTERVEN BY INJECTING CARBETOCIN OR OXYTOCIN INTRAMUSCULAR IMMEDIATELY FOLLOWING DELIVERY: ONE GROUP WILL RECEIVE CARBETOCIN 100 MCG IM OR GROUP 2 WILL RECEIVE 5 IU /10 IU IV IN

Eligibility

Inclusion criteria

Inclusion criteria: Inclusion Criteria : 1. Study will include pregnant women having vaginal delivery in our hospital . 2. Patient willing to be part of study. 3. Known singleton pregnancy .

Exclusion criteria

Exclusion criteria: Exclusion criteria : 1. Patient who undergo caesarean section . 2. Patient not willing to be include in study Ã¢â?¬â?? not giving consents. 3. Multiple pregnancies. 4. Patient having diabetes mellitus , IHCP,blood disorder ,hypertension ,or on any anticoagulant

Design outcomes

Primary

Measure	Time frame
To compare the efficacy of two oxytocics , namely carbetocin and oxytocin in active management of third stage of labor . we will give give oxytocic immediately following delivery of anterior shoulder of baby . we will see which oxytocics is more efficient , in term of onset of action , duration of action , preventention of PPH. Timepoint: we will give give oxytocic immediately following delivery of anterior shoulder of baby in normal vaginal delivery . we will see which oxytocics is more efficient , in term of onset of action , duration of action , preventention of PPH, amount of blood loss in normal vaginal delivery, . we will check all parameter with in 24 hour of delivery.	—

Measure

Time frame

To compare the efficacy of two oxytocics , namely carbetocin and oxytocin in active management of third stage of labor . we will give give oxytocic immediately following delivery of anterior shoulder of baby . we will see which oxytocics is more efficient , in term of onset of action , duration of action , preventention of PPH. Timepoint: we will give give oxytocic immediately following delivery of anterior shoulder of baby in normal vaginal delivery . we will see which oxytocics is more efficient , in term of onset of action , duration of action , preventention of PPH, amount of blood loss in normal vaginal delivery, . we will check all parameter with in 24 hour of delivery.

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Secondary

Measure	Time frame
To find out amount of blood loss in each group at the time of normal vaginal delivery . To find out change in hematocrit in each group (haemoglobin in third trimester and 24 hour after delivery ) To see the side effect in each group with in 24 hour To find out the requirement of a second dose of another oxytocics in each groups. Timepoint: To find out amount of blood loss in each group at the time of normal vaginal delivery . To find out change in hematocrit in each group (haemoglobin in third trimester and 24 hour after delivery ) To see the side effect in each group with in 24 hour To find out the requirement of a second dose of another oxytocics in each groups (during delivery ).	—

Measure

Time frame

To find out amount of blood loss in each group at the time of normal vaginal delivery . To find out change in hematocrit in each group (haemoglobin in third trimester and 24 hour after delivery ) To see the side effect in each group with in 24 hour To find out the requirement of a second dose of another oxytocics in each groups. Timepoint: To find out amount of blood loss in each group at the time of normal vaginal delivery . To find out change in hematocrit in each group (haemoglobin in third trimester and 24 hour after delivery ) To see the side effect in each group with in 24 hour To find out the requirement of a second dose of another oxytocics in each groups (during delivery ).

—

Countries

India

Contacts

Public ContactNEERU

MAX SMART SUPERSPECIALITY HOSPITAL , MANDIR MARG , PRESS ENCLAVE ROAD , SAKET , NEW DELHI 110017

drmanjukhemani@gmail.com9810611598

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026