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Role of Dexamethasone, Normal saline and Ketamine in prevention of post-operative sore throat.

Comparison of the effect of intracuff Normal saline, Dexamethasone or ketamine for prevention of post-operative sore throat: A randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/08/044664
Enrollment
405
Registered
2022-08-05
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K353- Acute appendicitis with localizedperitonitis

Interventions

Intervention1: Dexamethasone 0.2 mg/kg intra cuff in endotracheal tube: Use of Dexamethasone in preventing sore throat Control Intervention1: Ketamine 20 mg intracuff in endotracheal tube: Use of Keta

Sponsors

Priyabrat Karan
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All patients between age group 18 to 60 years without any allergic history

Exclusion criteria

Exclusion criteria: Patients refusing for trial and patients having allergy to drugs

Design outcomes

Primary

MeasureTime frame
Incidence and severity of post-operative Sore throatTimepoint: Incidence and severity of post-operative Sore throat at 2, 6, 12 & 24 hours after extubation—

Secondary

MeasureTime frame
Incidence and severity of post-operative hoarseness of voice and post-operative coughTimepoint: 2, 6, 12 & 24 hours after extubation—

Countries

India

Contacts

Public ContactPriyabrat Karan

AIIMS JODHPUR

ankuranaesthesia@gmail.com8279265105

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026