Health Condition 1: O- Medical and Surgical Health Condition 2: O- Medical and Surgical Health Condition 3: O- Medical and Surgical
Conditions
Interventions
Intervention1: Group A will receive propofol immediately after fentanyl administration.
: Propofol will be injected slowly at the rate of 1ml/3sec while communicating verbally with the patient. Induc
Sponsors
Sawai Mansingh Medical College and Hospital
Eligibility
Inclusion criteria
Inclusion criteria: ââ?? elective surgery under general anaesthesia ââ??¡age group 18 to 65 years ââ??¢ ASA I and 2 ââ??£ patient who gives written and informed consent in vernacular language
Exclusion criteria
Exclusion criteria: ââ?? patients refusing consent to participate in the study ââ??¡ patients allergic to propofol and/or fentanyl ââ??¢ obesity(bmi >30) ââ??£ anticipated difficult airway ââ??¤ Respiratory/cerebriovascular/cardiovascular and renal diseases including hypertension ââ??Â¥ receiving any drug likely to affect requirement of propofol and / or haemodynamic parameters. ââ??¦history of alcohol or drug use ââ??§ dehydration ââ??¨ emergency surgery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mean total dose of propofol Dose of propofol required per kg body weight for induction of general anaesthesiaTimepoint: Propofol is injected Immediately/ after 3minutes/ after 5minutes of fentanyl administration in 3 groups respectively | — |
Secondary
| Measure | Time frame |
|---|---|
| Mean systolic blood pressure Mean diastolic blood pressure Mean arterial pressure Mean heart rate Mean of proportion of cases experiencing hypotension, bradycardia and requirement of fluid boils and/or vasopressors Mean of proportion of cases of any movement, bucking and vocalisation during induction. Timepoint: These parameters are recorded every minute from baseline till 15 minutes after intubation | — |
Countries
India
Contacts
Public ContactDr Daisy Hazarika
SMS Medical College
Outcome results
None listed